Hidradenitis suppurativa treated with combination of infliximab and dapsone.
نویسندگان
چکیده
Hidradenitis suppurativa (HS) is chronic inflammatory disease characterized by recurrent painful nodules, which leads to forming an abscess and sinus tracts, together with pustulation and hypertrophic scarring in the areas of apocrine sweat glands. Systemic and local antibiotic therapy, together with corticoid therapy, sulphonates, retinoids and surgical treatment with incisions and drainage belongs to actual treatment possibilities. Biological therapy represents the absolute peak in the treatment last years, mostly TNFα-inhibitors. Even though their very good short term effect is described, long term keeping up the good long effect of the treatment is not achieved with satisfaction. This is the reason to reach for traditional therapeutic possibilities combined with biological treatment in cases of torpid and resistive disease. In the following article a case report of a patient with hidradenitis suppurativa treated subsequently with combination of TNFα-inhibitors and dapson (Fig. 6, Ref. 19).
منابع مشابه
[Hidradenitis suppurativa treated with infliximab].
Hidradenitis suppurativa is an inflammatory disease with difficult treatment. Currently, the anti-TNF alfa therapy, with monoclonal antibodies ('biological therapy'), has been shown as a new alternative. However, clinical trials assessing the efficacy of these drugs to treat hidradenitis suppurativa have not yet been published. A case in which the use of infliximab did not result in significant...
متن کاملSystemic therapy with immunosuppressive agents and retinoids in hidradenitis suppurativa: a systematic review.
Hidradenitis suppurativa (HS) is a difficult disease to treat. Although the pathogenesis of this inflammatory skin disease is largely unknown, the important role of the immune system has been demonstrated in both experimental and clinical studies. Clinicians are therefore increasingly prescribing systemic treatments with immunosuppressive agents, but the more traditionally used systemic retinoi...
متن کاملHidradenitis suppurativa treated with dapsone: A case series of five patients.
OBJECTIVE To evaluate the efficacy of dapsone in the treatment of hidradenitis suppurativa refractory to therapy with oral antibiotics and isotretinoin. METHODS A retrospective review was performed of five patients treated with dapsone between 2002 and 2005. Clinical improvement and adverse events were recorded by the physician. Patients were asked to retrospectively rate their symptoms prior...
متن کاملTreatment of hidradenitis suppurativa with infliximab in a patient with Crohn's disease.
BACKGROUND Hidradenitis suppurativa is a chronic, inflammatory, scarring disease characterized by recurrent flares. Recently, a group of 'autoinflammatory disorders' has been described. These disorders are characterized by recurrent inflammatory episodes not mediated by autoantibodies or antigen-specific T-cells. Some of these autoinflammatory disorders have been successfully treated with anti-...
متن کاملThe HSF MSAB Peer-Reviewed Database
s, american academy of dermatology, 64th annual meeting, march 3–7, 2006 san francisco, CA. J Am Acad Dermatol. 2006 Mar; 54(3):AB58. IM Ig as a treatment for suppurative disease. 2005 POSTER HS treated with Dapsone Gupta.pdf Gupta S, Taibjee S, Lewis H. Hidradenitis suppurativa treated with dapsone, a case series of six patients, BRISTOL CUP POSTER. Br J Dermatol. 2005 June; 153(S1):20-51. Six...
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ورودعنوان ژورنال:
- Bratislavske lekarske listy
دوره 113 5 شماره
صفحات -
تاریخ انتشار 2012